Detection of Highly Curved Membrane Surfaces Using a Cyclic Peptide Derived from Synaptotagmin-I
نویسندگان
چکیده
منابع مشابه
Vesicle-associated membrane protein-2/synaptobrevin binding to synaptotagmin I promotes O-glycosylation of synaptotagmin I.
Synaptotagmin I (Syt I), an evolutionarily conserved integral membrane protein of synaptic vesicles, is now known to regulate Ca2+-dependent neurotransmitter release. Syt I protein should undergo several post-translational modifications before maturation and subsequent functioning on synaptic vesicles (e.g. N-glycosylation and fatty acylation in vertebrate Syt I), because the apparent molecular...
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038 ©2011 Society For Biomaterials
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2012
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb3002705